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Running Head: ARTICLE REVIEW
This piece of literature fits the description of primary literature. Primary literature refers
to original research articles in which the authors have undertaken their study or experiment. The
authors, therefore, sought to determine the relationship between psychological stress and
vulnerability to respiratory viruses in a prospective study, where they deliberately exposed
subjects to viruses.
The hypothesis examined by this study is that physical stress suppresses one’s immune
response towards infection, including the common cold. This study aimed to determine whether
there is any relationship between documented clinical colds and the degree of psychological
stress in people exposed to respiratory viruses (Cohen et al., 1991).
The study design was an experimental, randomized, controlled, double-masked trial that
enrolled a total of 394 healthy subjects and administered nasal drops containing one of five
respiratory viruses (Novus type 2, Novus type 9, or The control group comprised of 26 subjects
who were administered saline nasal drops (Cohen et al., 1991). The expe …
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